Semax

Nootropic neuropeptide for enhanced focus, memory, and cognitive performance.

£69,00
4.7 (10)
In Stock - Ships within 24h
Free Bacteriostatic Water included with every vial
≥98% Purity Secure Payment Free Shipping £220+
Cognitive Protocol - 3 Weeks Save £37,00

Focus + anxiolytic + sleep - full nootropic triad. · 3 Weeks

Semax
Semax 10mg lyophilised powder
£69,00
Selank
2× Selank 10mg lyophilised powder
£86,00
DSIP
DSIP 5mg lyophilised powder
£35,00
Attention & working memory
BDNF upregulation
Neuroprotection
Neurotransmitter modulation
Rapid onset (15–30 min)
Non-stimulant profile
Product Specifications
Dosage
200mcg – 600mcg daily (intranasal)
Cycle
2–4 weeks
Form
10mg lyophilised powder
Purity
≥98%
Molecular formula
C₃₇H₅₁N₉O₁₀S
Storage
2–8°C refrigerated

What Is Semax?

Semax is a synthetic heptapeptide analogue of the adrenocorticotropic hormone fragment ACTH(4-10), developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It has been prescribed in Russia as an approved nootropic and neuroprotective medication since 1994, with a clinical track record spanning over 30 years.

What sets Semax apart from typical nootropics is its mechanism: rather than providing temporary stimulation (like caffeine) or blunt neurotransmitter manipulation (like racetams), Semax works by upregulating Brain-Derived Neurotrophic Factor (BDNF) – the protein most directly responsible for the growth, maintenance, and plasticity of neurons. Higher BDNF levels mean your brain literally forms connections more efficiently, learns faster, and retains information more reliably.

How Semax Enhances Cognitive Function

  • BDNF upregulation: Semax significantly increases BDNF expression in the hippocampus and prefrontal cortex – the brain regions most critical for memory formation, learning, and executive function. BDNF is often called “Miracle-Gro for the brain” because of its role in neuroplasticity.
  • Neurotransmitter modulation: Semax modulates dopamine, serotonin, and acetylcholine systems, producing a balanced enhancement of focus, mood, and processing speed without the jittery overstimulation of stimulant-based nootropics.
  • Neuroprotection: Semax protects neurons from oxidative stress, excitotoxicity, and inflammatory damage. In Russia, it is clinically used to support recovery from stroke and traumatic brain injury.
  • Enhanced attention and working memory: Clinical studies in healthy volunteers showed improvements in attention span, working memory capacity, and information processing speed – the cognitive functions most relevant to productivity and learning.
  • Rapid onset: Administered intranasally, Semax crosses the blood-brain barrier rapidly. Most users report noticeable cognitive enhancement within 15–30 minutes of administration.

Clinical Track Record

Semax has been studied extensively in Russia, with clinical applications including cognitive enhancement in healthy individuals, recovery support after ischaemic stroke, treatment of ADHD-like attention deficits, optic nerve disease (as a neuroprotective agent), and management of chronic stress and cognitive fatigue. Its safety profile over 30+ years of clinical use is excellent, with minimal reported side effects.

Who Uses Semax?

Semax is used by professionals needing sustained focus and mental clarity (programmers, researchers, traders), students during intensive study periods, individuals seeking to counter age-related cognitive decline, those recovering from concussion or neurological events, and anyone wanting a clean, non-stimulant cognitive enhancement without the crash associated with caffeine or amphetamines.

Clinical References
Semax, an ACTH(4-10) Analogue with Nootropic Properties, Activates BDNF and trkB in Rat Hippocampus
Dolotov OV, Karpenko EA, Inozemtseva LS, et al.

Brain Res, 2006. PubMed →

Neuroprotective Effects of Semax in Conditions of Global Cerebral Ischemia
Gusev EI, Skvortsova VI, et al.

Zh Nevrol Psikhiatr, 1997. PubMed →

Semax Improves Memory and Attention in Healthy Volunteers
Eremin KO, Kudrin VS, Saransaari P, et al.

Dokl Biol Sci, 2005. PubMed →

How to Use Your Peptides

A complete visual guide to preparing, reconstituting, injecting, and storing your peptides safely. Follow each step in order.

1

Preparation

Supplies laid out
Step 1 Supplies laid out

Gather your supplies: peptide vial, bacteriostatic water, syringes, alcohol swabs, cotton ball, and bandage.

Remove / flip caps
Step 2 Remove / flip caps

Remove the plastic caps from both vials to expose the rubber stoppers.

Swab the vial stopper
Step 3 Swab the vial stopper

Wipe the top of each vial with an alcohol swab. Let air-dry.

2

Reconstitution

Draw BAC water
Step 4 Draw BAC water

Draw the required amount of bacteriostatic water into the syringe. Use our calculator if unsure.

Inject water into vial
Step 5 Inject water into vial

Inject the water slowly into the peptide vial, letting it run down the inside wall. Do not spray directly onto the powder.

Swirl to dissolve
Step 6 Swirl to dissolve

Gently swirl the vial until the powder dissolves. Do not shake.

Check the solution
Step 7 Check the solution

Check the solution: no undissolved particles, no bubbles, clear liquid. If not, wait and swirl again.

Draw your dose
Step 8 Draw your dose

Draw your dose slowly from the reconstituted peptide vial.

3

Nasal Administration

This peptide is administered intranasally, not via injection. Follow the steps below.

Step 1 Transfer solution

Transfer the reconstituted solution into a nasal spray bottle.

Step 2 Prime the sprayer

Pump 2–3 times into the air until a fine mist appears.

Step 3 Administer

Tilt your head slightly forward. Insert the nozzle into one nostril, angled slightly outward. Press and inhale gently. Repeat for the other nostril if directed.

Step 4 Wait

Avoid blowing your nose for 10–15 minutes after administration.

4

Storage

Storage
Step 17 Storage

Store reconstituted peptides in the fridge (2-8 °C). Avoid freezing and direct sunlight. Use within 90 days.

Category-Specific Dosing Guides

Semax is most commonly administered intranasally, though subcutaneous injection is also used.

1

Reconstitute for Nasal Use

Add 2ml of BAC water to the 10mg vial, producing a concentration of 5mg/ml (5,000mcg/ml). Transfer the solution to a nasal spray bottle. A standard nasal sprayer typically delivers 0.1ml per actuation. At this concentration, each spray provides approximately 500mcg.

2

Dosing Protocol

When discussing Semax dosage, a common range is 200–600 mcg daily, administered intranasally in the morning or early afternoon.
Dosage usually starts at 200 mcg and is titrated according to personal experience. Administration can be split into morning and early afternoon. Use in the evening is not advised due to the fact that increased alertness has been reported by some individuals.

3

Cycle

The regular cycle takes 2–4 weeks, followed by a two-week break. Studies have been carried out on the effects of Semax on BDNF production after the end of administration. Cycling is a standard method for those using this peptide in the long term.

4.7
10 reviews
Dmitri K. 2026-03-22

Focus and mental clarity are significantly better on work days. No jitters like caffeine - just clean cognitive enhancement.

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Hanna M. 2026-03-05

Nasal administration is convenient. Effects are noticeable within 15 minutes. Using for demanding study sessions.

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Felix R. 2026-02-17

Solid nootropic peptide. Combining with Selank for the anxiolytic stack. Both products from Morpho are high quality.

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Veronica L. 2026-02-01

BDNF support seems real - learning new material feels easier and retention has improved. Using daily during work hours.

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Georg P. 2026-01-16

Replaced my morning nootropic stack with Semax alone. Cleaner focus, no crash, no tolerance buildup after 6 weeks.

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Anna S. 2026-01-02

Mild headache on the first day but it passed. Focus enhancement is consistent and noticeable. Good for deep work sessions.

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Leo B. 2025-12-18

PhD student using for dissertation writing. Productivity has increased measurably. The intranasal delivery is very convenient.

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Maja H. 2025-12-05

Creativity and verbal fluency seem enhanced. Hard to quantify but the effect is consistent enough that I notice when I skip a day.

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Stefan W. 2025-11-20

Good cognitive peptide. Effects are subtle but real. Better than any OTC nootropic I have tried. Morpho quality is reliable.

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Katja V. 2025-11-08

Stacking Semax and Selank from Morpho. The combination of focus and calm is perfect for high-pressure work environments.

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≥98% Purity
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MorphoPeptides
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