Epitalon

Telomerase-activating peptide for cellular rejuvenation and longevity support.

Price range: £43,00 through £341,00
4.7 (10)
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Free Bacteriostatic Water included with every vial
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Longevity Protocol - Standard (~8 wk) Save £171,00

Core longevity stack - cellular, skin, mitochondrial. · Standard (~8 wk)

Epitalon
10× Epitalon 10mg lyophilised powder
£430,00
GHK-Cu / Copper Peptide
2× GHK-Cu / Copper Peptide 50mg lyophilised powder
£138,00
MOTS-c
6× MOTS-c 10mg lyophilised powder
£312,00
Telomere length maintenance
Melatonin research
Antioxidant properties
Neuroendocrine regulation
Pineal gland function
Cellular aging research
Product Specifications
Dosage
5mg – 10mg daily
Cycle
10–20 days, repeated 2–3x yearly
Form
10mg lyophilised powder
Purity
≥98%
Molecular formula
C₁₄H₂₂N₄O₉
Storage
Room temperature (below 25°C)

What Is Epitalon?

Epitalon (also written as Epithalon or Epithalone) is a synthetic tetrapeptide consisting of four amino acids (Ala-Glu-Asp-Gly) based on the naturally occurring Epithalamin peptide produced by the pineal gland. Developed by Professor Vladimir Khavinson at the Saint Petersburg Institute of Bioregulation and Gerontology over 35 years of research, Epitalon is the most extensively studied peptide for its effects on telomerase activation and cellular longevity.

At its core, Epitalon targets one of the most fundamental mechanisms of biological aging: telomere shortening. Every time a cell divides, the protective caps on the ends of chromosomes (telomeres) get slightly shorter. When telomeres become critically short, the cell can no longer divide and enters senescence or dies. Epitalon activates telomerase – the enzyme that rebuilds telomere length – essentially helping to reset this biological clock.

How Epitalon Works: The Science of Telomeres

  • Telomerase activation: Epitalon’s primary mechanism is the activation of telomerase, the ribonucleoprotein enzyme that adds telomeric DNA (TTAGGG repeats) to the ends of chromosomes. By maintaining telomere length, cells retain their ability to divide and function normally for longer.
  • Pineal gland regulation: Epitalon stimulates the pineal gland to produce melatonin at more youthful levels. Melatonin production naturally declines with age, and restoring it improves sleep architecture, circadian rhythm regulation, and antioxidant defence.
  • Gene expression: Research has shown Epitalon can modulate gene expression patterns, activating genes associated with cellular repair and youth while dampening those associated with aging and senescence.
  • Antioxidant capacity: Epitalon enhances the body’s endogenous antioxidant systems, reducing oxidative stress – one of the primary drivers of cellular aging and damage.

Research & Legacy

Professor Khavinson’s research on Epitalon spans over three decades and includes human clinical studies. His work demonstrated that Epithalamin (the natural peptide Epitalon is based on) reduced mortality rates by 28% in an elderly population over a 12-year follow-up period. Laboratory studies showed Epitalon increased telomere length in human cells by activating the telomerase gene hTERT, and extended the lifespan of cell cultures beyond the Hayflick limit.

Beyond telomeres, users consistently report improved sleep quality, enhanced morning alertness, and a general sense of vitality during Epitalon cycles – likely mediated through its effects on melatonin and pineal gland function.

Who Uses Epitalon?

Epitalon appeals to anyone interested in longevity science and proactive aging support. It is popular among individuals over 35 who want to address cellular aging before visible signs appear, biohackers focused on optimising healthspan, and those experiencing age-related sleep deterioration who want a non-sedative approach to improving sleep quality.

Clinical References
Peptide Bioregulation of Aging: Results and Prospects
Khavinson VK

Adv Gerontol, 2020. PubMed →

Effect of Epithalon on Telomerase Activity and Telomere Length in Human Somatic Cells
Khavinson VK, Bondarev IE, Butyugov AA

Bull Exp Biol Med, 2003. PubMed →

Epitalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells
Khavinson VK, Bondarev IE, Butyugov AA, et al.

Neuro Endocrinol Lett, 2003. PubMed →

How to Use Your Peptides

A complete visual guide to preparing, reconstituting, injecting, and storing your peptides safely. Follow each step in order.

1

Preparation

Supplies laid out
Step 1 Supplies laid out

Gather your supplies: peptide vial, bacteriostatic water, syringes, alcohol swabs, cotton ball, and bandage.

Remove / flip caps
Step 2 Remove / flip caps

Remove the plastic caps from both vials to expose the rubber stoppers.

Swab the vial stopper
Step 3 Swab the vial stopper

Wipe the top of each vial with an alcohol swab. Let air-dry.

2

Reconstitution

Draw BAC water
Step 4 Draw BAC water

Draw the required amount of bacteriostatic water into the syringe. Use our calculator if unsure.

Inject water into vial
Step 5 Inject water into vial

Inject the water slowly into the peptide vial, letting it run down the inside wall. Do not spray directly onto the powder.

Swirl to dissolve
Step 6 Swirl to dissolve

Gently swirl the vial until the powder dissolves. Do not shake.

Check the solution
Step 7 Check the solution

Check the solution: no undissolved particles, no bubbles, clear liquid. If not, wait and swirl again.

Draw your dose
Step 8 Draw your dose

Draw your dose slowly from the reconstituted peptide vial.

3

Injection

Remove air bubbles
Step 9 Remove air bubbles

Hold the syringe needle-up, flick to move air bubbles to the top, and push the plunger until a small drop appears.

Choose injection site
Step 10 Choose injection site

Choose your injection site: belly fat around the navel or outer thigh. Rotate sites between injections.

Clean the site
Step 11 Clean the site

Clean the injection site with an alcohol swab.

Pinch skin
Step 12 Pinch skin

Pinch a fold of skin at the injection site to lift the subcutaneous fatty tissue away from the muscle.

Insert at 45°
Step 13 Insert at 45°

Insert the needle at a 45° angle into the subcutaneous fatty tissue, usually approximately half the needle length. Do not inject into muscle. Inject slowly.

4

Aftercare, Storage & Disposal

Cotton-ball press
Step 14 Cotton-ball press

Withdraw the needle and press a cotton ball gently on the site for a few seconds.

Apply bandage
Step 15 Apply bandage

Apply a small bandage.

Sharps disposal
Step 16 Sharps disposal

Dispose of the needle in a sharps container.

Storage
Step 17 Storage

Store reconstituted peptides in the fridge (2-8 °C). Avoid freezing and direct sunlight. Use within 90 days.

Category-Specific Dosing Guides

How to Use Epitalon It’s commonly used in short courses repeated several times throughout the year. Typical protocols involve 10–20 consecutive days of use, followed by several months without administration.

1

Reconstitute

Add 2ml of bacteriostatic (BAC) water to the 10mg vial to achieve a concentration of 5mg/ml. The lyophilized powder dissolves quickly and usually requires only a gentle swirl.

2

Dosing Protocol

Epitalon dosage protocol consists of 5–10mg daily for a sustained use over 10–20 days. Many users follow a protocol of 10mg daily for 20 days. Administration is generally performed via subcutaneous injection in the abdominal area.

3

Repeat 2–3 Times Per Year

Protocols are often repeated 2-3 times per year, with courses spaced approximately 4-6 months apart. Some users choose to schedule courses around seasonal transitions, such as spring and autumn.

4.7
10 reviews
Greta W. March 2026

Using for longevity research. Sleep quality improved noticeably in the first cycle. The science behind telomerase activation is fascinating.

Verified Purchase
Anton K. March 2026

Subtle effects but consistent. Skin elasticity seems better and overall recovery from workouts improved. On my second cycle.

Verified Purchase
Françoise D. February 2026

Hard to find quality Epitalon in Europe. Morpho delivers on purity and shipping speed. Recommended to my research group.

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Johan M. February 2026

Completed 3 cycles now. Sleep architecture has genuinely improved - deeper sleep and more consistent wake times.

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Renata C. January 2026

Interesting peptide for anti-aging. Skin tone appears more even and recovery from exercise has improved. Subtle but cumulative.

Verified Purchase
Wilhelm B. January 2026

The 10-day cycle protocol works well. Noticed improved wellbeing and energy by the second cycle. High purity product.

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Agnes L. December 2025

Longevity research is my focus. Epitalon from Morpho is the most reliable source I have found in the EU. COA checks out.

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Patrick O. December 2025

Started for sleep improvement, staying for the broader anti-aging benefits. Product quality is consistent across orders.

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Monika Z. November 2025

My naturopath recommended trying Epitalon. Glad I sourced it from Morpho - purity is verified and delivery was fast to Austria.

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Florian T. November 2025

On my fourth order. This has become a regular part of my longevity stack. Morpho is the only supplier I trust for this.

Verified Purchase

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